Package: curesurv 0.1.2

curesurv: Mixture and Non Mixture Parametric Cure Models to Estimate Cure Indicators

Fits a variety of cure models using excess hazard modeling methodology such as the mixture model proposed by Phillips et al. (2002) <doi:10.1002/sim.1101> The Weibull distribution is used to represent the survival function of the uncured patients; Fits also non-mixture cure model such as the time-to-null excess hazard model proposed by Boussari et al. (2020) <doi:10.1111/biom.13361>.

Authors:Juste Goungounga [aut, cre], Judith Breaud [aut], Olayide Boussari [aut], Laura Botta [ctb], Valerie Jooste [aut]

curesurv_0.1.2.tar.gz
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manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
curesurv/json (API)

# Install 'curesurv' in R:
install.packages('curesurv', repos = c('https://jgoungounga.r-universe.dev', 'https://cloud.r-project.org'))
Datasets:
  • dataweib - Simulated data with vital status information from Weibull mixture cure model
  • pancreas_data - Simulated pancreas data with vital status information
  • testiscancer - Simulated testis cancer data using a cure model

On CRAN:

Conda:

This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.

3.45 score 2 stars 14 scripts 291 downloads 4 exports 25 dependencies

Last updated from:4d61364e08. Checks:9 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-develOK178
source / vignettesOK202
linux-releaseOK167
macos-releaseOK132
macos-oldrelOK141
windows-develOK155
windows-releaseOK154
windows-oldrelOK143
wasm-releaseOK120

Exports:cumLexc_mulcuresurvz_alphaz_tau

Dependencies:bbmlebdsmatrixcliDerivFormulagluelatticelifecyclemagrittrMASSMatrixmvtnormnloptrnumDerivoptimxpracmarandtoolboxRcpprlangrngWELLstatmodstringistringrsurvivalvctrs

How to estimate a new mixture cure model for increased risk of non cancer death
Introduction | Installation | Fitting a classical mixture cure model in excess hazard modelling setting (M0) | Importing the dataset | Extracting the population background mortality from the French life table | Fitting a conventional mixture cure model with the uncured survival following a Weibull distribution | Fitting a new mixture cure model with the uncured survival (M1) allowing the background mortality to be corrected | How to select the best model | Plot of net survival, excess hazard and probability of being cured for the two models | Predictions by varying age values | Predictions by varying time since diagnosis and for age 50 and 70 | Session info | License | Acknowledgments | References

Last update: 2025-03-07
Started: 2024-09-18

Vignette_tneh
How to analyse survival data using Time-To-Null excess hazard model (TNEH model) | Additive hazard assumption in net survival setting | TNEH model | Instantaneous excess hazard | Cumulative excess hazard | Net survival | The cure fraction $\pi$ | The probability P(t) | Fit of tneh model using R | Without covariates | Prediction | Plot of different estimators (hazard, survival, probability of being cured conditionally on being alive) | Cure fraction estimation precision | Time-to-cure estimation | With covariates acting both on parameters tau and alpha | Predictions : | Plot of main indicators as a function of time for two patients of age mean and age max | Plot of the main indicators 2 years after diagnosis, for patients of varying ages | With covariates acting only on parameters adjusting the time-to-null excess hazard tau | Plot of excess hazard at varying times for 3 different ages at diagnosis (33.3, 51.6, 69,1) | With covariates acting only on scale parameter alpha | Predictions | Plot of estimation of probability P(t) of being cured at a given time t after diagnosis knowing that he/she was alive up to time t | Comparing models | Session info

Last update: 2024-09-18
Started: 2024-09-18